Volume 5 Issue 2
Dec.  2021
Turn off MathJax
Article Contents
Jianjun Wu, Guiqiu Shan, Maohong Bian, Xin Cui, Guoliang Ding, Yahan Fan, Jianping Li, Zhongjun Li, Jiubo Liu, Hua Lu, Qun Luo, Shijie Mu, Mei Qin, Haiyan Wang, Jiang Wu, Daiquan Xia, Rong Xia, Pu Xu, Guihua Yang, Wen Yin, Zebo Yu, Juan Zhang, Lili Zhu, Peiyuan Zhu, Jiwu Gong, Shuming Zhao. Guideline for the collection and preparation of non-transfusion autologous platelet concentrate or platelet-rich plasma from patients in hospitals[J]. Blood&Genomics, 2021, 5(2): 73-82. doi: 10.46701/BG.2021022021128
Citation: Jianjun Wu, Guiqiu Shan, Maohong Bian, Xin Cui, Guoliang Ding, Yahan Fan, Jianping Li, Zhongjun Li, Jiubo Liu, Hua Lu, Qun Luo, Shijie Mu, Mei Qin, Haiyan Wang, Jiang Wu, Daiquan Xia, Rong Xia, Pu Xu, Guihua Yang, Wen Yin, Zebo Yu, Juan Zhang, Lili Zhu, Peiyuan Zhu, Jiwu Gong, Shuming Zhao. Guideline for the collection and preparation of non-transfusion autologous platelet concentrate or platelet-rich plasma from patients in hospitals[J]. Blood&Genomics, 2021, 5(2): 73-82. doi: 10.46701/BG.2021022021128

Guideline for the collection and preparation of non-transfusion autologous platelet concentrate or platelet-rich plasma from patients in hospitals

doi: 10.46701/BG.2021022021128
More Information
  • Corresponding author: Jiwu Gong, Department of Blood Transfusion, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China. E-mail: 13910066259@139.com; Shuming Zhao, Department of Blood Transfusion, Guiqian International General Hospital, Guiyang, Guizhou 550018, China. E-mail: shumingzhao123@qq.com
  • Received Date: 2021-10-18
  • Accepted Date: 2021-11-19
  • Rev Recd Date: 2021-11-01
  • Available Online: 2022-01-06
  • Publish Date: 2021-12-31
  • Non-transfusion autologous platelet concentrate (PC), also known as platelet-rich plasma (PRP), has become a widely used blood-based product in the field of sports medicine, rehabilitation medicine, and clinical medicine. Currently, autologous PC or PRP operation procedures (personnel qualification, equipment, methods, environment and tracking, protocols, preparations, techniques and product quality control) lack unified specifications and standards, which lead to inconsistencies in the quality of PC or PRP products made by medical institutions, affecting treatment efficiency. In blood collection and supply organizations, the collection of blood components has a series of standard operating procedures (SOP) and quality assurance which can be referenced by medical institutions to standardize the preparation and usage of patient autologous PC or PRP products. According to Technical Standards for Preparation of Platelet Concentrate for Blood Stations, we compiled this guideline for medical staff to prepare high quality and reliable PC or PRP products in order to promote the standardization of PC or PRP in clinical application.

     

  • loading
  • [1]
    Working party on clinical transfusion management, Chinese Society of Blood Transfusion (CSBT). Expert consensus on preparation technique of autologous platelet-rich plasma[J]. Chin J Blood Transfus, 2021, 34(7): 677−683. doi: 10.13303/j.cjbt.issn.1004-549x.2021.07.001
    [2]
    Magaziner E, Vandenbosch J, Harshfield D, et al. Guidelines for the use of platelet rich plasma[EB/OL]. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.467.2101&rep=rep1&type=pdf
    [3]
    Chawla K, Mittal S and Kumar K. A systematic review of platelet-rich plasma in the management of upper limb tendinopathies[J]. Eng Transl Med, 2017, 28(3): 224−232. doi: 10.1007/s40883-017-0042-y
    [4]
    Stolla M, Kapur R, Semple J. New emerging development of platelets in transfusion medicine[J]. Transfus Med Rev, 2020, 34(4): 207−208. doi: 10.1016/j.tmrv.2020.09.009
    [5]
    Al-Riyami AZ, Jug R, Rocca UL, et al. Quality of evidence‐based guidelines for platelet transfusion and use: a systematic review[J]. Transfusion, 2021, 61(3): 948−958. doi: 10.1111/trf.16257
    [6]
    Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)[J]. Trends Biotechnol, 2009, 27(3): 158−167. doi: 10.1016/j.tibtech.2008.11.009
    [7]
    Everts P A, Devilee R, Mahoney CB, et al. Exogenous application of platelet-leukocyte gel during open subacromial decompression contributes to improved patient outcome. A prospective randomized double-blind study[J]. Eur Surg Res, 2008, 40(2): 203−210. doi: 10.1159/000110862
    [8]
    Li D, Wang Y, Shen Y. A randomized study protocol comparing the platelet-rich plasma with hyaluronic acid in the treatment of symptomatic knee osteoarthritis[J]. Medicine, 2021, 100(2): e23881. doi: 10.1097/MD.0000000000023881
    [9]
    Karasavvidis T, Totlis T, Gilat R, et al. Platelet-rich plasma combined with hyaluronic acid improves pain and function compared with hyaluronic acid alone in knee osteoarthritis: a systematic review and meta-analysis[J]. Arthroscopy, 2021, 37(4): 1277−1287. doi: 10.1016/j.arthro.2020.11.052
    [10]
    Longjam DS, Akoijam JS, Ahongshangbam MS, et al. Comparison of the clinical effect of intra-articular injection of platelet-rich plasma and methylprednisolone in primary osteoarthritis of knee: a randomized controlled trial[J]. Int J Adv Med, 2019, 6(6): 1842−1848. doi: 10.18203/2349-3933.ijam20195238
    [11]
    Jo CH, Lee SY, Yoon KS, et al. Allogeneic platelet-rich plasma versus corticosteroid injection for the treatment of rotator cuff disease: a randomized controlled trial[J]. J Bone Joint Surg Am, 2020, 102(24): 2129−2137. doi: 10.2106/JBJS.19.01411
    [12]
    Xiong BJ, Tan QW, Chen YJ, et al. The effects of platelet-rich plasma and adipose-derived stem cells on neovascularization and fat graft survival[J]. Aesthetic Plast Surg, 2018, 42(1): 1−8. doi: 10.1007/s00266-017-1062-1
    [13]
    Wu J, Jiang B, Xiang R, et al. A massive dose of allogeneic platelet gel for wound hemostatic therapy on patients with giant thoracic aortic aneurysm: report of 2 cases[J]. Blood Genom, 2021, 5(1): 57−62. doi: 10.46701/BG.2021012021105
    [14]
    Jo CH, Lee SY, Yoon KS, et al. Allogenic pure platelet-rich plasma therapy for rotator cuff disease: a bench and bed study[J]. Am J Sports Med, 2018, 46(13): 3142−3154. doi: 10.1177/0363546518800268
    [15]
    Asadi M, Alamdari D, Rahimi H, et al. Treatment of life-threatening wounds with a combination of allogenic platelet-rich plasma, fibrin glue and collagen matrix, and a literature review[J]. Exp Ther Med, 2014, 8(2): 423−429. doi: 10.3892/etm.2014.1747
    [16]
    Anitua E, Prado R, Orive G. Allogeneic platelet-rich plasma: at the dawn of an off-the-shelf therapy[J]. Trends Biotechnol, 2017, 35(2): 91−93. doi: 10.1016/j.tibtech.2016.11.001
    [17]
    Rainys D, Cepas A, Dambrauskaite K, et al. Effectiveness of autologous platelet-rich plasma gel in the treatment of hard-to-heal leg ulcers: a randomised control trial[J]. J Wound Care, 2020, 28(10): 658−667. doi: 10.12968/jowc.2019.28.10.658
    [18]
    Picard F, Hersant B, Bosc R, et al. The growing evidence for the use of platelet‐rich plasma on diabetic chronic wounds: a review and a proposal for a new standard care[J]. Wound Repair Regen, 2015, 23(5): 638−643. doi: 10.1111/wrr.12317
    [19]
    O'Connell B, Wragg NM, Wilson SL. The use of PRP injections in the management of knee osteoarthritis[J]. Cell Tissue Res, 2019, 376(2): 143−152. doi: 10.1007/s00441-019-02996-x
    [20]
    Theys T, Van Hoylandt A, Broeckx CE, et al. Plasma-rich fibrin in neurosurgery: a feasibility study[J]. Acta Neurochir (Wien). 2018; 160(8): 1497–1503.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(1)

    Article Metrics

    Article views (175) PDF downloads(11) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return