Evaluation of Erythrocyte-Magnetized Technology in the Detection of Irregular Antibodies

This study aims to evaluate the application value of erythrocyte-magnetized technology in the detection of irregular antibodies. A total of 10 113 patients requiring blood transfusion were selected for the detection of irregular antibodies by microcolumn gel test and erythrocyte-magnetized technology simultaneously. The saline solution method and in-tube indirect antihuman globulin test were used as reference comparisons. Their ability to detect low titer antibodies was evaluated. A total of 72 antibody-positive samples were detected with a detection rate of 91.67% by microcolumn gel test and 84.72% by erythrocyte-magnetized technology. IgG antibody detection ability was consistent; however, IgM antibody detection ability was significantly lower. Both of them had considerably low titer antibody detection ability. This study suggests that erythrocyte-magnetized technology could serve as a valuable platform for irregular antibody analysis in clinic.